Biotechnology Stocks I: Compare Returns to S&P 500 to Spyre Therapeutics, Inc. (SYRE)

Biotechnology Stocks I: Compare Returns of S&P 500 to Spyre Therapeutics, Inc. (SYRE)

S&P 500 prices are represented by SPDR® S&P 500® ETF (SPY) prices.

Prices for SPY and the designated stock are monthly closes adjusted for splits and dividends from Alpha Vantage.

Compare Returns for SPY and SYRE
Start DateMay-31-2016May-31-2016
Start Price$177.24$187.50
End DateJul-09-2025Jul-09-2025
End Price$624.06$16.55
Number Monthly Prices111111
Min DateMay-31-2016May-31-2023
Min Price$179.66$3.25
Max DateJul-09-2025Aug-31-2018
Max Price$624.06$273.25
Total Return247.36%-91.17%
Annualized Return14.41%-23.08%
Current Value of $1,000 Purchase$3,474$88
Number Returns6,1056,105
Average Return56.04%-26.14%
Minimum Return-23.93%-98.81%
Maximum Return247.36%1,067.98%
Number Profitable Returns5,7461,795
Percent Profitable Returns94.12%29.40%
Number Unprofitable Returns3594,310
Percent Unprofitable Returns5.88%70.60%
Profitable to Unprofitable Returns Ratio16.010.42






SYRE Performance Table and Chart

SYRE Dollar-cost Average

SYRE Correlation with S&P 500

SYRE Trendline Chart

SYRE Moving Average Chart

SYRE Stock Return Map - See Patterns of Gains and Losses

SYRE Stock Returns/Purchase Dates